South America
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Jerry Friedman: The Commonwealth is clearly in the southern hemisphere, and there are far more suggestions of South America than of Africa or Australasia, but I don't think we're supposed to connect it with the real present-day South America, still less connect the mountains with the Andes or Nessus with Buenos Aires.
Interesting! The debate does carry on after all. I would agree with the assessment that there are far more S. America references than to any other geographic location on earth. This includes extant and fossil animals and human cultural references.
So I guess the question becomes: if Wolfe didn't intend us to associate the Commonwealth with South America why did he use such an overwhelming volume of South American references?